Nos publications
Platform technology for introducing liquid solubilizers in tablet formulations
AAPS - oct 2024
Lipid-based excipients, which are often liquid at room temperature, can enhance solubility and permeation. This study aims to incorporate a liquid lipid excipient into a solid dosage form for the poorly water-soluble drug ondansetron hydrochloride dihydrate (OHD).
Advantages of combining polymers and lipids in extrusion processes
PBP - mar 2024
Lipid excipients lower the glass transition temperature of polymers, enabling hot-melt extrusion at lower engine torque for better processability. Different polymers and lipid combinations have been tested to explore their potential in extrusion processes.
Impact of Granulation Solvent on Release Performance of Dual Matrix Extended-Release Tablets of Highly Water Soluble Drugs Formulated using Compritol® 888 ATO and Methocel® as Release Retarding Agents
AAPS PharmSci360 – Boston (USA) - oct 2022
The purpose of this study is to evaluate the impact of different granulation solvents on the performance of dual extended- release matrix tablets, formulated using a combination of Compritol® 888 ATO and Methocel® K100M, with two model APIs:
- highly water-soluble high dose (1000 mg) Metformin Hydrochloride
- freely water-soluble low dose (95 mg) Metoprolol Succinate
Exploring the Potential of Compritol® 888 ATO for Abuse Deterrent Sustained Release Tablets
CRS Annual Meeting – Montreal (Canada) - jui 2022
Selecting efficient pharmaceutical binder for developing robust extended-release matrices of Compritol® 888 ATO prepared using wet granulation technique: Part 2 Studying impact on dissolution profiles of ER tablets of different API’s
CRS Annual Meeting - virtual - jui 2021
Selecting efficient pharmaceutical binder for developing robust extended-release matrices of Compritol® 888 ATO prepared using wet granulation technique: Part 1 Studying impact on granule & tablet properties
CRS Annual Meeting - virtual - jui 2021
Selecting efficient pharmaceutical binder for developing robust extended-release matrices of Compritol® 888 ATO prepared using wet granulation technique: Part 1 Studying impact on granule & tablet properties
CRS Annual Meeting - virtual - jui 2021
Evolution of the Microstructure of Sustained-release Matrix Tablets during Dissolution and Storage
Indian J Pharm Sci 2018;80(6):1011-1020 - sep 2018
QbD - How particle size and glyceride composition affect the performance of sustained-release tablets with Compritol 888 ATO
AAPS Annual Meeting & Exposition – San Diego (USA) - nov 2017