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In this section, you will learn more about Gattefossé Pharmaceuticals expertise, through news, hot topics and publications at the cutting edge of science, you can browse through a library of on-demands webinars, and download our latest brochures.
Nouveautés et sujets d'actualité
Transcutol® V, your ally for formulating veterinary medicines
This excipient is a must when it comes to the formulation of veterinary medicines, as it can be used for oral, topical, and parenteral dosage forms.
The basics of intestinal permeation
Improving the oral bioavailability of pharmaceuticals is a challenging task, heavily influenced by the solubility and permeability of the active pharmaceutical ingredient. Intestinal permeation enhancers, such as medium chain fatty acid esters, play a crucial role in this context by facilitating the passage of drugs through the intestinal barrier, thus improving their absorption and therapeutic efficacy.
Harnessing lipids as plasticizers in hot-melt extrusion: a gateway to innovation
Unlocking a new opportunity to use lipid excipients
Nos dernières publications
Unveiling the Potential of Labrasol® ALF Labrafac™ MC60 and Capryol® 90 as Permeation Enhancers to Address Low Bioavailability Issues
oct 2024
In vitro, ex vivo, and in vivo tests show that Labrasol® ALF, Labrafac™ MC60, and Capryol® 90 are effective and safe permeation enhancers. They work by temporarily opening tight junctions in the intestinal lining, potentially improving the bioavailability of poorly permeable drugs, including small molecules (BCS III and IV) and large molecules like peptides and proteins.
Platform technology for introducing liquid solubilizers in tablet formulations
oct 2024
Lipid-based excipients, which are often liquid at room temperature, can enhance solubility and permeation. This study aims to incorporate a liquid lipid excipient into a solid dosage form for the poorly water-soluble drug ondansetron hydrochloride dihydrate (OHD).
