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Nouveautés et sujets d'actualité
Transcutol® V, your ally for formulating veterinary medicines
This excipient is a must when it comes to the formulation of veterinary medicines, as it can be used for oral, topical, and parenteral dosage forms.
The basics of intestinal permeation
Improving the oral bioavailability of pharmaceuticals is a challenging task, heavily influenced by the solubility and permeability of the active pharmaceutical ingredient. Intestinal permeation enhancers, such as medium chain fatty acid esters, play a crucial role in this context by facilitating the passage of drugs through the intestinal barrier, thus improving their absorption and therapeutic efficacy.
Harnessing lipids as plasticizers in hot-melt extrusion: a gateway to innovation
Unlocking a new opportunity to use lipid excipients
Nos dernières publications
A QbD-based UPLC-ELSD method for quantifying medium-chain triglycerides in Labrafac™ WL 1349 for nanoemulsion applications
jan 2025
This article showcases the development and validation of a robust UPLC-ELSD method, using analytical Quality-by-Design principles, to accurately quantify medium-chain triglycerides in a lipid-based excipient for nanoemulsion applications, ensuring compliance with regulatory standards.
Understanding Microemulsions and Nanoemulsions in (Trans)Dermal Delivery
jan 2025
Microemulsions and nanoemulsions are explored in pharmaceuticals for their potential in delivering clinically relevant drug doses across biological membranes. Despite extensive literature, there's a lack of clear distinctions between the two in terms of definitions and mechanisms: this review aims to uncover less obvious yet important mechanisms in transdermal drug delivery.
