Nos publications
Structural and thermal characterization of glyceryl behenate by X-ray diffraction coupled to differential calorimetry and infrared spectroscopy
International Journal of Pharmaceutics, Volume 336, Issue 2, Pages 248-256 - mai 2007
MODIFICATION OF THE DRUG RELEASE OF IBUPROFEN BY HOT-MELT COATING WITH MIXES OF COMPRITOL® 888 ATO AND NON-IONIC SURFACTANTS
AAPS Annual Meeting – Nashville (USA) - 2005
Comparative study of the lubricant performance of Compritol®888 ATO either used by blending or by hot melt coating
International Journal of Pharmaceutics. Volume 262, Issues 1–2, Pages 39–45 https://doi.org/10.1016/S0378-5173(03)00027-9 - aou 2003
In this study, the lubricant performance of Compritol 888 ATO is assessed in a classical blending process or by hot melt coating. The results suggest that the hot melt coating process induces an homogeneous repartition of the lubricant on the lactose surface,
contrary to classical blending procedure. Thus, lubrication by hot melt coating seems to be a very efficient procedure. It could be used specifically for large surface area particulate systems producing a lot of friction.
Comparative study of the lubricant performance of Compritol® HD5 ATO and Compritol® 888 ATO: effect of polyethylene glycol behenate on lubricant capacity
International Journal of Pharmaceutics. Volume 254, Issue 2, Pages 263–269 https://doi.org/10.1016/S0378-5173(03)00027-9 - mar 2003
In this study the lubricant capacity of Compritol HD5 ATO is compared to Compritol 888 ATO. It shows that mixing lubricants with Lactopress present no structural differences and that they have equivalent compressibility and cohesiveness. This study concludes
that Compritol HD5 ATO could be a very interesting excipient because it associates the glyceryl dibehenate lubricant capacity with the polyethylene glycol property of enhanced dissolution.