Nos publications
Comparing the effect of adding Gelucire® 48/16 and Gelucire® 50/13 in amorphous solid dispersion: a case study with ticagrelor
CRS - jui 2024
When amorphous solid dispersion (ASD) are produced by hot melt extrusion (HME), the use of a neat polymer requires high process temperatures, and the drug release is not always complete. Adding Gelucire® in the formula is a promising strategy to address these issues.
Advantages of combining polymers and lipids in extrusion processes
PBP - mar 2024
Lipid excipients lower the glass transition temperature of polymers, enabling hot-melt extrusion at lower engine torque for better processability. Different polymers and lipid combinations have been tested to explore their potential in extrusion processes.
The Gelucire® family
Pharma Excipients - 2018
Structural and Thermal Characterization of Mono- and Diacyl Polyoxyethylene Glycol by Infrared Spectroscopy and X-ray Diffraction Coupled to Differential Calorimetry
J. Phys. Chem. B, 108, 46, 17721–17729 - oct 2004
STRUCTURAL AND THERMAL CHARACTERISATION OF LIPIDIC EXCIPIENTS AND CARRIERS BY X-RAY DIFFRACTION COUPLED TO DIFFERENTIAL MICROCALORIMETRY
Académie des Alpilles, Bulletin Technique Gattefossé N°97 - jan 2004