Nos publications

Understanding Microemulsions and Nanoemulsions in (Trans)Dermal Delivery

  • Scientific publication

AAPS PharmSciTech - jan 2025

Jasmine Musakhanian, David W. Osborne

Microemulsions and nanoemulsions are explored in pharmaceuticals for their potential in delivering clinically relevant drug doses across biological membranes. Despite extensive literature, there's a lack of clear distinctions between the two in terms of definitions and mechanisms: this review aims to uncover less obvious yet important mechanisms in transdermal drug delivery.

A systematic approach to formulate and evaluate the stability of topical creams with high concentrations of Transcutol® HP

  • Poster

AAPS PharmSci 360 – Washington DC (USA)  - nov 2018

Masumi Dave, M.S., Jason Le Pree, Ph.D., R.Ph. – Gattefossé USA

In this study the authors developped stable anhydrous and hydrous creams containing 40% Transcutol® HP, using predictive techniques to select appropriate excipients. 

Skin Penetration and Permeation Properties of Transcutol®—Neat or Diluted Mixtures

  • Scientific publication

AAPS PharmSciTech, Vol. 19, No.8 DOI: 10.1208/s12249-018-1196-8 - nov 2018

David W. Osborne and Jasmine Musakhanian

In this critical article, the authors have reviewed numerous studies in order to elucidate the mechanism of action of the highly purified diethylene glycol monoethyl ether TRANSCUTOL® on skin penetration and permeation.