Nos publications

Toward improving the in vitro in vivo correlation of lipid-based formulations using a simplified gastro-intestinal lipolysis protocol

  • Poster

AAPS - oct 2024

Elise Dauphin-Chanard, Stéphanie Chevrier, Malaury Ducros, Philippe Caisse

Lipid-based formulations (LBF) enhance the oral bioavailability of poorly water-soluble drugs by maintaining them in a solubilized state during digestion. This study aims to establish a robust protocol to evaluate the impact of gastro-intestinal lipolysis on LBF performance, using cinnarizine as a model drug.

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In vitro lipolysis tests on lipid nanoparticles: comparison between lipase/co-lipase and pancreatic extract.

  • Scientific publication

Drug Development and Industrial Pharmacy - Volume 41 - Issue 10 https://doi.org/10.3109/03639045.2014.972412 - 2015

Jannin V, Dellera E Chevrier S, Chavant Y, Voutsinas C, Bonferoni C, Demarne F.

Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase

  • Scientific publication

Pharmaceutical Research volume 32, pages 1279–1287 DOI: 10.1007/s11095-014-1532-y  - avr 2015

Bakala-N’Goma, J.C., Williams, H.D., Sassene, P., Kleberg, K., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Müllertz, A., Pouton, C.W., Porter, C.J.H., Carrière, F.

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Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 6: Effects of Varying Pancreatin and Calcium Levels.

  • Scientific publication

The AAPS Journal, volume 16, pages 1344–1357 DOI: 10.1208/s12248-014-9672-x - nov 2014

Sassene, P.J., Kleberg, K., Williams, H.D., Bakala-N’Goma, J.C., Carrière, F., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Porter, C.J.H., Pouton, C.W., Müllertz, A.

In vitro lipolysis study of nanoparticulate delivery systems: solid lipid nanoparticles and nanostructured lipid carriers

  • Poster

AAPS Annual Meeting and Exposition – San Antonio (USA)  - nov 2013

V. JANNIN, E. DELLERA, S. CHEVRIER, Y. CHAVANT, C. VOUTSINAS, C. BONFERONI, F. DEMARNE

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In Vitro Digestion of the Self-Emulsifying Lipid Excipient Labrasol® by Gastrointestinal Lipases and Influence of its Colloidal Structure on Lipolysis Rate

  • Scientific publication

Pharmaceutical Research volume 30, pages 3077–3087 DOI: 10.1007/s11095-013-1053-0 - mai 2013

Sylvie Fernande, Vincent Jannin, Stéphanie Chevrier, Yann Chavant, Frédéric Demarne, Frédéric Carrière

In vitro lipolysis of the self-emulsifying excipient, Labrasol®

  • Poster

AAPS Annual Meeting & Exposition – San Diego (USA)  - nov 2007

Sylvie FERNANDEZ, Nicolas RITTER, Stéphanie CHEVRIER, Frédéric CARRIÈRE and Vincent JANNIN

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The fate of some pharmaceutical surfactants during in vitro lipolysis and the effect on solubilization of a poorly soluble model compound

  • Poster

CRS Annual Meeting  - 2006

Anne Larsen, Dimitris G. Fatouros, Alma Bibuljica, Vincent Jannin, Anette Müllertz

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