Nos publications

Size characterization of commercial micelles and microemulsions by Taylor dispersion analysis

  • Scientific publication

International Journal of Pharmaceutics, Volume 492, Issues 1–2, Pages 46-54 - aou 2015

Joseph Chamieh, Florian Davanier, Vincent Jannin, Frédéric Demarne, Hervé Cottet

In vitro lipolysis tests on lipid nanoparticles: comparison between lipase/co-lipase and pancreatic extract.

  • Scientific publication

Drug Development and Industrial Pharmacy - Volume 41 - Issue 10 https://doi.org/10.3109/03639045.2014.972412 - 2015

Jannin V, Dellera E Chevrier S, Chavant Y, Voutsinas C, Bonferoni C, Demarne F.

Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase

  • Scientific publication

Pharmaceutical Research volume 32, pages 1279–1287 DOI: 10.1007/s11095-014-1532-y  - avr 2015

Bakala-N’Goma, J.C., Williams, H.D., Sassene, P., Kleberg, K., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Müllertz, A., Pouton, C.W., Porter, C.J.H., Carrière, F.

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Biorelevant media resistant co-culture model mimicking permeability of human intestine.

  • Scientific publication

International Journal of Pharmaceutics, Volume 481, Issues 1–2, Pages 27-36 - mar 2015

Delphine Antoine, Yann Pellequer, Camille Tempesta, Stefan Lorscheidt, Bernadette Kettel, Lana Tamaddon, Vincent Jannin, Frédéric Demarne, Alf Lamprecht, Arnaud Béduneau

Cell culture models are currently used to predict absorption pattern of new compounds and formulations in the human gastro-intestinal tract (GIT). One major drawback is the lack of relevant apical incubation fluids allowing mimicking luminal conditions in the GIT. Here, we suggest a culture model compatible with biorelevant media, namely Fasted State Simulated Intestinal Fluid (FaSSIF) and Fed State Simulated Intestinal Fluid (FeSSIF).

Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 6: Effects of Varying Pancreatin and Calcium Levels.

  • Scientific publication

The AAPS Journal, volume 16, pages 1344–1357 DOI: 10.1208/s12248-014-9672-x - nov 2014

Sassene, P.J., Kleberg, K., Williams, H.D., Bakala-N’Goma, J.C., Carrière, F., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Porter, C.J.H., Pouton, C.W., Müllertz, A.

A tunable Caco-2/HT29-MTX co-culture model mimicking variable permeabilities of the human intestine obtained by an original seeding procedure

  • Scientific publication

European Journal of Pharmaceutics and Biopharmaceutics, Volume 87, Issue 2, Pages 290-298 https://doi.org/10.1016/j.ejpb.2014.03.017 - jui 2014

Arnaud Béduneau, Camille Tempesta, Stéphane Fimbel, Yann Pellequer, Vincent Jannin, Frédéric Demarne , Alf Lamprecht

In vitro lipolysis study of nanoparticulate delivery systems: solid lipid nanoparticles and nanostructured lipid carriers

  • Poster

AAPS Annual Meeting and Exposition – San Antonio (USA)  - nov 2013

V. JANNIN, E. DELLERA, S. CHEVRIER, Y. CHAVANT, C. VOUTSINAS, C. BONFERONI, F. DEMARNE

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Influence of intestinal biorelevant fluids on a novel co-culture cell model able to mimic varaible permeabilities of the human intestine

  • Poster

AAPS Annual Meeting and Exposition – San Antonio (USA)  - 2013

C. TEMPESTA, A. BÉDUNEAU, V. JANNIN, Y. PELLEQUER, F. DEMARNE, A. LAMPRECHT

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In Vitro Digestion of the Self-Emulsifying Lipid Excipient Labrasol® by Gastrointestinal Lipases and Influence of its Colloidal Structure on Lipolysis Rate

  • Scientific publication

Pharmaceutical Research volume 30, pages 3077–3087 DOI: 10.1007/s11095-013-1053-0 - mai 2013

Sylvie Fernande, Vincent Jannin, Stéphanie Chevrier, Yann Chavant, Frédéric Demarne, Frédéric Carrière