Nos publications
Gelucire® 48/16: a solid surfactant for tablets
Pharma Times, Vol. 48 – N° 11 – pp 17-22 - nov 2016
This article describes Gelucire® 48/16 – a novel pegylated lipid excipient, and its use as a solid surfactant for solubility enhancement.
Impact of hot and wet granulation techniques on Compritol® 888 ATO lipid matrices for extended release of highly water soluble high dose API
CRS Annual Meeting – Seattle (2016) - 2016
The poster describes the formulation of sustained release tablets with Metformin HCl (a well-known oral antihyperglycemic) using Compritol® 888 ATO as a sustained release agent. Different granulation techniques were evaluated to elucidate the impact of formulation and process on tablet properties and drug release. The objective was to determine a simple process that enables the production of ‘smaller’ tablets, using less excipients, whilst maintaining therapeutic drug dose and obtaining drug release which passes Pharmacopeial specifications.