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22 résultat(s)

Keratinocyte stem cells are more resistant to UVA radiation than their direct progeny

  • Article scientifique

PLOS ONE - 2018

Elodie Metral, Nicolas Bechetoille, Frédéric Demarne, Odile Damour, Walid Rachidi

Keratinocyte stem cells, which are responsible for epidermal renewal throughout life, are equipped with an efficient arsenal against several genotoxic agents.

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Mitochondrial damage and cytoskeleton reorganization in human dermal fibroblasts exposed to artificial visible light similar to screen-emitted light

  • Article scientifique

Journal of Dermatological Science - 2018

Adeline Rascalou, Jérôme Lamartine, Pauline Poydenot, Frédéric Demarne, Nicolas Bechetoille

Artificial visible light induces drastic molecular and cellular changes in normal human fibroblasts.

Harmful effects of screen-emitted artificial visible light in dermis: an additional environmental stress not to be neglected

  • Poster

IID - 2018

Adeline Rascalou , Frédéric Demarne PhD, Nicolas Bechetoille PhD

We have investigated the effects of artificial visible light in human dermal fibroblasts and we described a patented plant extract of Withania somnifera root able to protect those skin cells.

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α6 Integrin/Transferrin receptor (CD71) low keratinocyte stem cells are more potent for generating reconstructed skin epidermis than rapid adherent cells

  • Article scientifique

International Journal of Molecular Sciences - 2017

Elodie Metral, Nicolas Bechetoille, Frédéric Demarne, Walid Rachidi, Odile Damour

Cells isolated by a rapid adherent method are not the same population as keratinocytes stem cells isolated by flow cytometry following α6high/CD71low phenotype.

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Long-term genoprotection effect of Sechium edule fruit extract against UVA irradiation in keratinocytes

  • Article scientifique

Photochemistry and Photobiology - 2017

Elodie Metral, Walid Rachidi, Odile Damour, Frédéric Demarne, Nicolas Bechetoille

The objective of this study was to investigate the effects of a Sechium edule fruit extrac in terms of photoprotection against UVA in primary human keratinocytes.

Distinct photoprotective effects on UVA irradiated-keratinocytes

  • Article scientifique

Journal of Investigative Dermatology - 2016

N. Bechetoille, E. Metral, F. Demarne, O. Damour, W. Rachidi

Using different techniques enable to explore cellular responses against UVA stress and to demonstrate the photoprotective effects of products against UV irradiation.

A multiparametric, stepwise in vitro approach to identify anti-dark circle and anti-puffiness ingredients

  • Poster

IFSCC Congress - 2022

C. Lorion PhD, C. Lavastre, A. Rascalou, A. Lopez-Gaydon, S. Bonnet, T. Rinaldi, V. Charton, B. Vogelgesang, N. Bechetoille PhD

A unique plant extract with promising anti-puffiness and anti-dark circle potential has been identified using the stepwise selection model.

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Advanced translational cosmetics: using the world’s first non-invasive bioimpedance 3D bioprinted skin chips to link cosmetics lab testing to humans

  • Poster

IFSCC Congress - 2022

McGuckin, Bechetoille, Legues, Milet, Besseyre, Boyer, Ferrier, Sanchez, Forraz, Vogelgesang

This model enables advanced translational lab-to-donor data to help bring sophisticated cosmetics ingredients to market faster, safely and more affordably.

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A NaDES extract of Rose ‘Jardin de Granville®’ displays pro-resolving and epidermal strengthening properties

  • Poster

IFSCC Congress - 2022

Pecher V., Franchi J., Charton V., Dubourdeau M, Van Goethem E., Baillif V., Nizard C., Choisy P., Vogelgesang B., Bechetoille N.

The fructose/propanediol/water (NaDES FPW113) extract of “Jardin de Granville” Rose flowers has demonstrated great potential in vitro and ex vivo to support epidermal homeostasis and counteract the inflammaging process.

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