Nos publications
Comparing the effect of adding Gelucire® 48/16 and Gelucire® 50/13 in amorphous solid dispersion: a case study with ticagrelor
CRS - jui 2024
When amorphous solid dispersion (ASD) are produced by hot melt extrusion (HME), the use of a neat polymer requires high process temperatures, and the drug release is not always complete. Adding Gelucire® in the formula is a promising strategy to address these issues.
Advantages of combining polymers and lipids in extrusion processes
PBP - mar 2024
Lipid excipients lower the glass transition temperature of polymers, enabling hot-melt extrusion at lower engine torque for better processability. Different polymers and lipid combinations have been tested to explore their potential in extrusion processes.
Gelucire® 48/16: a safe wetting agent for tablet. A case study with fenofibrate
CRS Annual Meeting – Montreal (Canada) - jui 2022
Gelucire 48/16® for Type-IV Lipid Based Formulations and Their In Vitro In Vivo Performance Evaluation
AAPS PharmSci360 – San Antonion (USA) - nov 2019
A Novel Approach To Prepare Solid Self-microemulsifying Drug Delivery System Without A Solid-phase Carrier Using 3D Printing
CRS Annual Meeting – New York (USA) - jui 2018
Bioavailable Curcumin – A Type 4 Lipid Based Drug Delivery System Using Gelucire®48/16 As Solid Solubilizer
CRS Annual Meeting – New York (USA) - jui 2018
The Gelucire® family
Pharma Excipients - 2018
Macrogol esters: Influence on in vitro and in vivo dissolution of a poorly soluble drug
AAPS Annual Meeting & Exposition – San Diego (USA) - nov 2017
Gelucire 48/16®: A Non-Ionic Solid Surfactant for Solubility Enhancement of Poorly Soluble Drugs
AAPS Annual Meeting & Exposition – San Diego (USA) - nov 2017