Nos publications

In-vitro investigation regarding the effects of Gelucire® 44/14 and Labrasol® ALF on the secretory intestinal transport of P-gp substrates

  • Scientific publication

International Journal of Pharmaceutics, Volume 515, Issues 1–2, Pages 293-299 https://doi.org/10.1016/j.ijpharm.2016.10.012 - déc 2016

Océane Dubray, Vincent Jannin, Fréderic Demarne, Yann Pellequer, Alf Lamprecht, Arnaud Béduneau

Solidification of liquid self-emulsifying lipid formulations by loading on solid mesoporous carriers

  • Poster

PBP World Meeting 2016 – Glasgow (Scotland)  - nov 2016

Vincent Jannin; Stéphanie Chevrier; Cédric Miolane; Margaux Metin; Hamza Benhaddou; Yann Chavant; Fred Monsuur; Frédéric Demarne

Télécharger (.pdf - 734.62 Ko)

Gelucire® 48/16: a solid surfactant for tablets

  • Whitepaper

Pharma Times, Vol. 48 – N° 11 – pp 17-22  - nov 2016

Ketkee Deshmukh and Chhanda Kapadia

This article describes Gelucire® 48/16 – a novel pegylated lipid excipient, and its use as a solid surfactant for solubility enhancement. 

Solid State Structural Aspects of Solid Self-microemulsifying Drug Delivery Systems (sSMEDDS) during Digestion

  • Poster

AAPS Annual Meeting & Exposition – Denver (USA)  - nov 2016

Kapilkumar Vithani, Vincent Jannin, Colin Pouton, Ben J. Boyd

Télécharger (.pdf - 886.9 Ko)

Compritol® 888 ATO: a sustained release lipid matrix for once a day aceclofenac tablets

  • Poster

AAPS Annual Meeting & Exposition – Denver (USA)  - nov 2016

C. J. Kapadia, A. R. Shrivastava, G. R. Khanvilkar

Télécharger (.pdf - 896.33 Ko)

Converting simple microemulsion into attractive foam for topical pain treatment. A case study with lidocaine base

  • Poster

AAPS Annual Meeting & Exposition – Denver (USA)  - nov 2016

E Dauphin-Chanard, C André and D Marchaud

Télécharger (.pdf - 982.75 Ko)

Converting light emulsion into a creamy foam for psoriasis treatment. A case study with betamethasone dipropionate

  • Poster

AAPS Annual Meeting & Exposition – Denver (USA)  - nov 2016

E Dauphin-Chanard, C André and D Marchaud

Télécharger (.pdf - 978.03 Ko)

Experience foam for topical drug delivery

  • Whitepaper

nov 2016

Gattefossé

Pharmaceutical foams are becoming more popular probably due to more topical medicines being switched to OTC and the need to innovate and differentiate ‘brands’ and an increasing awareness of the importance of formulating to deliver sensorial benefits and positive impact on patient experience and adherence. Gattefossé, as a leading provider of excipients for the pharmaceutical industry, manufactures solubilizers and texturizers for skin drug delivery. In this white paper we give formulation tips for propellant and propellant-free foams with guidelines on how to formulate and select excipients and case studies with model drugs. 

Télécharger (.pdf - 480.71 Ko)

Hydrodynamic size characterization of a self-emulsifying lipid pharmaceutical excipient by Taylor dispersion analysis with fluorescent detection

  • Scientific publication

International Journal of Pharmaceutics, Volume 513, Issues 1–2, Pages 262-269 - nov 2016

Vincent Jannin, Frédéric Demarne, Hervé Cottet

In this study the size of microemulsion droplets is carried out using Tailor Dispersion Analysis in comparison to Dynamic Light Scattering. The size evolution of a Labrasol® self emulsifying drug delivery system as a function of concentration and temperature is evaluated. The influence of physical parameters and polydispersity is discussed.