Nos publications

Solubilisation behaviour of poorly water-soluble drugs during digestion of solid SMEDDS

  • Scientific publication

European Journal of Pharmaceutics and Biopharmaceutics, Volume 130, Pages 236-246 - sep 2018

Kapilkumar Vithani, Adrian Hawley, Vincent Jannin, Colin Pouton, Ben J. Boyd

A Novel Approach To Prepare Solid Self-microemulsifying Drug Delivery System Without A Solid-phase Carrier Using 3D Printing

  • Poster

CRS Annual Meeting – New York (USA)  - jui 2018

KapilkumarVithani, Alvaro Goyanes, Vincent Jannin, Simon Gaisford, Ben Boyd

Evaluation of spray-congealing to obtain a solid SEDDS

  • Poster

PBP World Meeting – Granada (Spain)  - 2018

Trung Quan TRAN, Odile CHAMBIN, Vincent JANNIN, Dominique CHAMPION, Rémi SAUREL, Philippe CAYOT

Inclusion of digestible surfactants in solid SMEDDS formulation removes lag time and influences the formation of structured particles during digestion

  • Scientific publication

The AAPS Journal, Vol. 19, No. 3 - mai 2017

Kapilkumar Vithani, Adrian Hawley, Vincent Jannin, Colin Pouton, Ben J. Boyd

The objective of this study is to evaluate how solid self-microemulsifying drug delivery systems (SMEDDS) behave during digestion. SMEDDS containing Gelucire® 44/14 and surfactants were prepared and their dispersion and digestion behaviors were studied using an in vitro lipolysis model, coupled with small-angle X-ray scattering (SAXS) to determine the formed colloidal structures during digestion in real time.

The study shows that the lipid to surfactant ratio has a significant effect on the kinetics of digestion and an optimum ratio is prerequisite to develop rapidly digestible solid SMEDDS system.

Solidification of liquid self-emulsifying lipid formulations by loading on solid mesoporous carriers

  • Poster

PBP World Meeting 2016 – Glasgow (Scotland)  - nov 2016

Vincent Jannin; Stéphanie Chevrier; Cédric Miolane; Margaux Metin; Hamza Benhaddou; Yann Chavant; Fred Monsuur; Frédéric Demarne

Solid State Structural Aspects of Solid Self-microemulsifying Drug Delivery Systems (sSMEDDS) during Digestion

  • Poster

AAPS Annual Meeting & Exposition – Denver (USA)  - nov 2016

Kapilkumar Vithani, Vincent Jannin, Colin Pouton, Ben J. Boyd

Interest of carriers for the development of solid self-emulsifying drug delivery systems

  • Poster

PBP World Meeting  - 2006

Vincent Jannin; Stéphanie Chevrier; Cédric Miolane; Margaux Metin; Hamza Benhaddou; Yann Chavant; Fred Monsuur; Frédéric Demarne