Hard fat pessary base delivering enhanced spreadability within the vaginal cavity and good mechanical resistance. Non-irritant providing excellent mucosal tolerance.
Names & synonyms
| USP NF Name | Mixture of hard fat, glyceryl ricinoleate and ethoxylated fatty alcohols |
|---|---|
| EP Name | Mixture of hard fat, glyceryl ricinoleate and ethoxylated fatty alcohols |
| UNII Code (FDA) | 8334LX7S21 ZUE0CEL42O YRC528SWUY |
| Preferred Substance Name (FDA) | Hard fat glyceryl ricinoleate Polyoxyl 20 cetostearyl ether |
| Handbook of Pharmaceutical Excipients | / |
| Chemical description | Consists of a mixture of mono-, di- and triglyceride esters of fatty acids (C10 to C18), the triester fraction being predominant and esters of ricinoleic (C18:1) acid and ethoxylated fatty alcohols |
Key characteristics
| Product form | Pellets |
|---|---|
| Melting range (°C) | 31.5 - 33.0 |
| Hydroxyl value (mg KOH/g) | 60 - 70 |
Main functionalities
Good mechanical resistance. Enhanced spreadability of the formulation for vaginal delivery.
Main formulation technologies
Pessary molding.
Documentation
Documentation technique
Associated content
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