Opting for the best emulsifier, as a function of the formulation

Tefose® 63

• Versatile: can be used with a wide range of drugs 
• Range of viscosity, including fluid, foam, or rich cream 
• Use at 5%–20% (w/w) 
• Outstanding mucosal tolerance 
• One-pot manufacturing process feasible 

Gelot™ 64

• Ideal for difficult-to formulate APIs (e.g., alcohol extracts, acidic drugs, and essential oils) 
• Forms rich creams and balms over a wide pH range 
• Use at 2%–12% (w/w) 
• Can emulsify anhydrous phase (PEG, glycerin) 
• Suitable for anti-acne drugs (tretinoin, azelaic acid) 

Plurol® Diisostearique

• Liquid excipient ideal for heat-sensitive APIs when used in cold emulsification process 
• PEG-free emulsifier 
• Non-irritant; suitable for sensitive skin 
• Forms rich creams when used at 3%–6% (w/w) 
• W/O emulsification: up to 85% of aqueous phase 

Tefose® 1500

• Versatile: can be used with a wide range of drugs 
• Recommended for sprays and lotions 
• Use at 5%-10% (w/w) 

Apifil® 

• Ideal for formulations with high oil content  
• Compatible with a wide variety of oils. 
• Compatible with most APIs at pH between 4.5 and 7.0. 
• Recommended for sticks 

Sedefos™ 75 

• Ideal for water sensitive APIs 
• Suitable for anhydrous formulations 
• Recommended for balms and foams 
• Compatible with all oily phases (up to 40%). 
• One pot process is feasible when amount of Sedefos™ 75 ≥ 9%.