A nonionic water-in-oil emulsifier for topical emulsions. A PEG-free liquid emulsifier ideal for cold formulation processes with heat sensitive APIs.
Names & synonyms
| USP NF Name | Polyglyceryl-3 diisostearate |
|---|---|
| EP Name | Triglycerol diisostearate |
| UNII Code (FDA) | 46P231IQ |
| Preferred Substance Name (FDA) | POLYGLYCERYL-3 DIISOSTEARATE |
| Handbook of Pharmaceutical Excipients | / |
| Chemical description | Consits of polyglyceryl-3 esters of stearic (C18) acid, the diester fraction being predominant |
Key characteristics
| Product form | Liquid |
|---|---|
| HLB | 4.5 |
Main functionalities
PEG-free W/O emulsifier for topical formulations Ideal for heat-sensitive API Stabilizes and improves sensorial and texture properties Safety of use is supported by precedence of use in approved pharmaceutical products
Main formulation technologies
Topical cream. Cold formulation process.
Documentation
Documentation technique
Associated content
Opting for the best emulsifier, as a function of the formulation
Our emulsifiers are all-in-one self-emulsifying bases, enabling the preparation of…
Developing patient-friendly textures
Improvement of topical dosage form texture and sensorial properties is an…