Precirol® ATO 5

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A glyceride with an intermediate melting point used as lubricant and flow aid in powder blends for capsule filling and as a coating agent for taste masking.

Names & synonyms

USP NF Name

Glyceryl distearate
EP Name

Glycerol distearate (type I)
UNII Code (FDA)

73071MW2KM
Preferred Substance Name (FDA)

GLYCERYL DISTEARATE
Handbook of Pharmaceutical Excipients

Glyceryl palmitostearate
Chemical description

Consists of esters of palmitic (C16) and stearic (C18) acids, the diester fraction being predominant

Key characteristics

Product form

Powder
Melting range (°C)

50 - 60
HLB

2

Main functionalities

Coating agent for taste masking. Lubricant and flow aid for capsule filling with powders. Modified release matrix former for tablets. Safety of use is inferred by GRAS status and precedence of use in approved pharmaceutical products.

Main formulation technologies

Tablet compression (direct and wet granulation). Powder-filled capsules. Melt processes: granulation, extrusion, coating, prilling, spray congealing. Nanoparticle formulation.

Documentation

Documentation technique

Brochures

Scientific document

Associated content

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