All publications

Bigels: case studies of an innovative topical dosage form

  • Poster

ABCF Congress - Nov 2024

Delphine Pélisson, Manon Rossano, Paulo Cunha, Kelly Bueno, Philippe Caisse, Elise Dauphin-Chanard

Adherence to treatments is a key challenge for topical formulations. Bigels, formulated with Emulfree® Duo are an innovative dosage form that can combine both hydrophilic and lipophilic active ingredients in a stable, moisturizing, and easily spreadable formulation. This study showcases three different placebo bigels formulations.

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Precision Engineering of Lipid-Based Nanosystems via Impingement Jet Mixing

  • Poster

PBP - Mar 2024

M. Zettl, C. Tetyczka, C. Glader, R. Jeitler, S. Stephan, M. Segl, Y. Wang, P. Caisse, V. Bourgeaux, M. Spoerk, E. Roblegg, J. Khinast

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Formulation Components' Role in Shaping Continuous Nanocarrier Production through Impingement Jet Mixing

  • Poster

PBP - Mar 2024

C. Tetyczka, M. Zettl, C. Glader, R. Jeitler, S. Stephan, M. Segl, Y. Wang, P. Caisse, V. Bourgeaux, M. Spoerk, J. Khinast, E. Roblegg

Flash nanoemulsification with impingement jet mixing is a technique used to produce nanocarriers. This study optimized the nanocarrier formulation to facilitate the manufacturing process and monitoring.

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Implementation of an at-line nanoparticle size analyzer in a continuous nano-manufacturing line considering critical measurement and process conditions

  • Poster

PBP - Mar 2024

C. Glader, R. Jeitler, N. Cacic, Y. Wang, C. Tetyczka, M. Zettl, J. Khinast, M. Rossano, S. Mesite, M. Lübbert, E. Roblegg

Nanopharmaceuticals' size is a critical quality attribute. This work provides insights about the implementation of an at-line particle size analyzer in a continuous manufacturing line of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC).

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Formulating pharmaceutical topical dosage forms with high level of solvents and minimal quantity of water

  • Poster

PBP - Mar 2024

Delphine Pélisson, Elise Dauphin-Chanard

This poster dives into the formulation of topical dosage forms containing the maximum amount of solvent and the minimum amount of water, while ensuring their stability upon storage.

Download (.pdf - 287.97 KB)