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In this section, you will learn more about Gattefossé Pharmaceuticals expertise, through news, hot topics and publications at the cutting edge of science, you can browse through a library of on-demands webinars, and download our latest brochures.

News and hot topics

Transcutol® V, your ally for formulating veterinary medicines

  • Animal Health

This excipient is a must when it comes to the formulation of veterinary medicines, as it can be used for oral, topical, and parenteral dosage forms.

Transcutol bottle

The basics of intestinal permeation

  • Intestinal permeation enhancers

Improving the oral bioavailability of pharmaceuticals is a challenging task, heavily influenced by the solubility and permeability of the active pharmaceutical ingredient. Intestinal permeation enhancers, such as medium chain fatty acid esters, play a crucial role in this context by facilitating the passage of drugs through the intestinal barrier, thus improving their absorption and therapeutic efficacy.

Harnessing lipids as plasticizers in hot-melt extrusion: a gateway to innovation

  • Hot melt extrusion

Unlocking a new opportunity to use lipid excipients

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Webinars

Boosting Oral Drug Permeability with Colloidal Carriers and Tight Junction Modulation

  • Intestinal permeation enhancers

This webinar will cover strategies to enhance the oral permeability of poorly soluble drugs and peptides using colloidal carriers and tight junction modulation.

intestines purple

Sustained Release Redefined: Lipid-Based Matrices as a Versatile Platform

  • Modified-release

This webinar will explore the unique release mechanisms of lipid matrices, specifically those formulated with Compritol® 888 ATO (glyceryl dibehenate).

Latest Publications

Bigels: case studies of an innovative topical dosage form

  • Poster

Nov 2024

Adherence to treatments is a key challenge for topical formulations. Bigels, formulated with Emulfree® Duo are an innovative dosage form that can combine both hydrophilic and lipophilic active ingredients in a stable, moisturizing, and easily spreadable formulation. This study showcases three different placebo bigels formulations.

Unveiling the Potential of Labrasol® ALF Labrafac™ MC60 and Capryol® 90 as Permeation Enhancers to Address Low Bioavailability Issues

  • Whitepaper

Oct 2024

In vitro, ex vivo, and in vivo tests show that Labrasol® ALF, Labrafac™ MC60, and Capryol® 90 are effective and safe permeation enhancers. They work by temporarily opening tight junctions in the intestinal lining, potentially improving the bioavailability of poorly permeable drugs, including small molecules (BCS III and IV) and large molecules like peptides and proteins.

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All brochures

Gattefosse Brochure Safe and efficient skin drug delivery

  • Brochure

  • Topical/Transdermal
Gattefosse Brochure Safe and efficient skin drug delivery

Gelucire 44/14

  • Brochure

Learn how to use this self-emulsifying excipient to increase oral drug bioavailability

  • Oral
Download (.pdf - 2.14 MB)
gelucire-44-14_self-emulsifying-excipient-for-solubility-and-oral-bioavailability-enhancement
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