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Transcutol® V, your ally for formulating veterinary medicines

Animal Health

This excipient is a must when it comes to the formulation of veterinary medicines, as it can be used for oral, topical, and parenteral dosage forms.

The basics of intestinal permeation

Intestinal permeation enhancers

Improving the oral bioavailability of pharmaceuticals is a challenging task, heavily influenced by the solubility and permeability of the active pharmaceutical ingredient. Intestinal permeation enhancers, such as medium chain fatty acid esters, play a crucial role in this context by facilitating the passage of drugs through the intestinal barrier, thus improving their absorption and therapeutic efficacy.

Harnessing lipids as plasticizers in hot-melt extrusion: a gateway to innovation

Hot melt extrusion

Unlocking a new opportunity to use lipid excipients

Webinars

Boosting Oral Drug Permeability with Colloidal Carriers and Tight Junction Modulation

Intestinal permeation enhancers

This webinar will cover strategies to enhance the oral permeability of poorly soluble drugs and peptides using colloidal carriers and tight junction modulation.

Sustained Release Redefined: Lipid-Based Matrices as a Versatile Platform

Modified-release

This webinar will explore the unique release mechanisms of lipid matrices, specifically those formulated with Compritol® 888 ATO (glyceryl dibehenate).

Latest Publications

Veterinary soft chews using Gelucire® 50/13 and Precirol® ATO 5. A proof of concept with wet extrusion

Poster

Mar 2025

This study aims to demonstrate the effectiveness of Gelucire® 50/13, a surfactant, and Precirol® ATO 5, a taste-masking agent, in producing veterinary soft chews using a wet extrusion process. These ingredients enable the development of high-drug load formulations with taste-masking capabilities and customizable drug release profiles, making them ideal for this innovative dosage form.

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In Vitro In Silico Correlation of Lidocaine HCl Skin Permeation - A Comparative Study of Gel Cream and Bigel formulations

Poster

Mar 2025

In this work, the effectiveness of Skin-in-Silico™ software for simulating dermal absorption and permeation of lidocaine hydrochloride in gel, cream, and bi-gel forms was evaluated. By combining in silico predictions with in vitro experiments, we explore the correlation between these methods and their role in optimizing topical drug formulations.

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