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Hydrodynamic size characterization of a self-emulsifying lipid pharmaceutical excipient by Taylor dispersion analysis with fluorescent detection

  • Scientific publication

International Journal of Pharmaceutics, Volume 513, Issues 1–2, Pages 262-269 - Nov 2016

Vincent Jannin, Frédéric Demarne, Hervé Cottet

In this study the size of microemulsion droplets is carried out using Tailor Dispersion Analysis in comparison to Dynamic Light Scattering. The size evolution of a Labrasol® self emulsifying drug delivery system as a function of concentration and temperature is evaluated. The influence of physical parameters and polydispersity is discussed.