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Eyeglorius™

Brilliance with every blink

Eyeglorius™ is a liposoluble bioactive designed to correct dark circles and puffiness and restore a re-energized and glorious look.

Groomed for Greatness

Textures & Formulation

21 Nov 2024 Reading : 2mn

Address common beard concerns like dryness, itchiness, and dandruff with Gattefossé…

Hair care

Portrait of a father with his son, both with mustaches

Color Pulse: New Makeup Collection

News
Personal care

24 Oct 2024 Reading : 2mn

Gattefossé strengthens its position in makeup with its latest collection of formulas.

Personal care

Construction of spheroids from melanocytes of different ethnic origins: screening model and variation

Publication
Poster

Sep 2024

Melanogenesis is a complex porcess, ans its in vitro modeling remains a challenge to develop relevant test suitable for rapid preclinical evaluation of the efficacy of lightening products to modulate human skin pigmentation.
Melanocytes are known to lose their ability to synthesize melanin in monolayer culture, even though the melanin content correlates with the ethnic background of the donors. Tissue engineering is an alternative to 2D culture because the cell behaviors in 3D microenvironment are closer to skin physiology.
We therefore compared the efficacy of 3 assays as high-throughput in vitro systems for skin-lightening drug screening: (i) Monolayer 2D culture of proliferative melanocytes, (ii) Microtissue 3D spheroid of non-proliferative melanocytes, (iii) Epidermal tissue 3D model containing functional melanocytes.

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