All publications
Understanding Microemulsions and Nanoemulsions in (Trans)Dermal Delivery
AAPS PharmSciTech - Jan 2025
Microemulsions and nanoemulsions are explored in pharmaceuticals for their potential in delivering clinically relevant drug doses across biological membranes. Despite extensive literature, there's a lack of clear distinctions between the two in terms of definitions and mechanisms: this review aims to uncover less obvious yet important mechanisms in transdermal drug delivery.
Rheology as a tool for characterizing topical product formulations: impact of solubilizer variation on stability and structure
CRS - Jul 2024
The use of solubilizers in a topical formulation helps solubilization of poorly soluble APIs. Therefore, it is essential to have a formulation chassis that can be modulated to incorporate this quantity of solubilizer. In this poster, the influence of different excipients as solubilizers and their variation on the stability and rheological properties of topical creams is investigated.
Establishment of a binary phase diagrams database for the development of self-emulsifying lipid-based formulations
AAPS Annual Meeting and Exposition – San Diego (USA) - 2014
Self-formulation protocol: Part II: excipient selection, diagram design and selection of prototype formulations.
AAPS Annual Meeting and Exposition - San Antonio (USA) - Nov 2013
Dispersion test and ternary diagramming are detailed, to determine the excipient ratios and prototype formulations
Self-formulation protocol: Part III: impact of lipolysis on prototype formulations
AAPS Annual Meeting and Exposition - San Antonio (USA) - 2013
Lipolysis test is used to determine the capacity of prototype formulations to maintain drug in solubilized state.
Self-formulation protocol: Part I: Solubility determination in liquid and solid excipients
AAPS Annual Meeting and Exposition – San Antonio (USA) - 2013
Dispersion test and ternary diagramming are detailed, to determine the excipient ratios and prototype formulations