All publications

Platform technology for introducing liquid solubilizers in tablet formulations

• Poster

AAPS - Oct 2024

Ketkee Deshmukh, Vitthal N. Gadlawar, Devanshi S. Shah, Swapnil Mohurle, Sunil Bambarkar

Lipid-based excipients, which are often liquid at room temperature, can enhance solubility and permeation. This study aims to incorporate a liquid lipid excipient into a solid dosage form for the poorly water-soluble drug ondansetron hydrochloride dihydrate (OHD).

Gelucire® 48/16: a safe wetting agent for tablet. A case study with fenofibrate

• Poster

CRS Annual Meeting – Montreal (Canada)  - Jul 2022

E. Dauphin-Chanard ; JM. Girard ; C. Deleglise ; P. Caisse

Gelucire 48/16®: A Versatile Non-Ionic Solid Solubilizer for Tablets of Poorly Water-Soluble Drugs

• Poster

AAPS PharmSci360 – Washington DC (USA)  - Nov 2018

Agnivesh Shrivastava, Ketkee Deshmukh, Nabil Farah, Sharda Gurram, Sunil Bambarkar

A solid dispersion of ticagrelor and Gelucire® 48/16 is prepared to increase drug solubility . The solid dispersion is converted into tablets. The formulated tablets showed improved dissolution rate compared to the market reference. 

Gelucire 48/16®: A Non-Ionic Solid Surfactant for Solubility Enhancement of Poorly Soluble Drugs

• Poster

AAPS Annual Meeting & Exposition – San Diego (USA)  - Nov 2017

Chhanda Kapadia, Agnivesh Shrivastava, Sharda Gurram

Macrogol esters: Influence on in vitro and in vivo dissolution of a poorly soluble drug

• Poster

AAPS Annual Meeting & Exposition – San Diego (USA)  - Nov 2017

Chhanda Kapadia, Meenakshi Venkataraman, Megha Marwah , Nabil J Farah , M.S. Nagarsenker

Gelucire® 48/16: a solid surfactant for tablets

• Whitepaper

Pharma Times, Vol. 48 – N° 11 – pp 17-22  - Nov 2016

Ketkee Deshmukh and Chhanda Kapadia

This article describes Gelucire® 48/16 – a novel pegylated lipid excipient, and its use as a solid surfactant for solubility enhancement.