All publications
Bioavailable Curcumin – A Type 4 Lipid Based Drug Delivery System Using Gelucire®48/16 As Solid Solubilizer
CRS Annual Meeting – New York (USA) - Jul 2018
High shear coating: a versatile taste-masking process
ONdrugDelivery Magazine, Issue 88, pages 10-13 - Jul 2018
Copyright © 2018 Frederick Furness Publishing Ltd
Development of a daphnetin transdermal patch using chemical enhancer strategy: insights of the enhancement effect of Transcutol P and the assessment of pharmacodynamics.
Drug Dev Ind Pharm. 2018 Oct;44(10):1642-1649. doi: 10.1080/03639045.2018.1483391. Epub 2018 Jul 2. - Jul 2018
A patch for transdermal delivery of daphnetin was developed using Transcutol® P as permeation enhancer.
The study showed:
10% Transcutol® P led to a significant increase in drug release from the patch.
Patch exhibited analgesic and anti-inflammatory activity
Evaluation of spray-congealing to obtain a solid SEDDS
PBP World Meeting – Granada (Spain) - 2018
The Gelucire® family
Pharma Excipients - 2018
Improving patient experience with sensorial topical dosage forms
PBP World Meeting – Granada (Spain) - 2018
Gels, crèmes, formes semi-solides : de leur développement à leur enregistrement. [Gels, creams, semi-solid forms: from their development to their registration]
STP Pharma Pratiques – September October 2018 – 28(5) 181-250 – ISSN 1157-1497 - 2018
The SFSTP commission on topical dosage forms published an article reviewing all the steps for their development to registration.
Interestingly this article is both in French and English languages.
Table of content:
Introduction
I Definition of a semi-solid
II Tests and studies applicable in evaluation of semi-solid forms from development up to the phase of routine use
2.1 Regulatory requirements
2.2 Relevant tests in development
2.2.1 Conventional characterization tests
2.2.2 Characterization tests specified to evaluate performance of the formulation
2.2.3 Additional characterization tests specified to evaluate performance of the formulation
III QbD approach related to the formulation
3.1 Different elements of the QbD
3.2 When to set up QbD ?
3.3 Definition of QTPP
3.4 CQAs toward evaluation of risks of process
3.5 Example of CMAs studied in case of a semi-solid formulation
3.6 Example of CPPs studied in case of a semi-solid formulation
Conclusion
IV Conclusions and perspectives
Complex Interplay between Solubilization, Digestion, Supersaturation and Absorption of Poorly Soluble Drugs with Lipid-Based Formulations
Current Drug Delivery, 2018, 15, 749-751 - 2018
Lipid-based nanosuspensions for oral delivery of peptides, a critical review
International Journal of Pharmaceutics, Volume 541, Issues 1–2, Pages 117–135 - Apr 2018
In this review article, the authors describe:
the different techniques used to prepare Solid Lipid Nanoparticles and Nanostructured Lipid Carriers
the methods used to assess the protective effects of the carriers on peptides
the techniques used to measure the permeability enhancement