A thixotropic suspension vehicle for pharmaceutical APIs. Ready-to-use in a cold process for thermosensitive actives in soft gel capsule.
Names & synonyms
| USP NF Name | Mixture of refined soybean oil USP-NF, glyceryl distearate USP-NF and polyglyceryl-3 dioleate USP-NF |
|---|---|
| EP Name | Mixture of refined soybean oil EP, glyceryl distearate EP and polyglyceryl-3 dioleate |
| UNII Code (FDA) | 241ATL177A 73071MW2KM XRQ165498B |
| Preferred Substance Name (FDA) | Soybean oil Glyceryl distearate Polyglyceryl-3 oleate |
| Handbook of Pharmaceutical Excipients | Soybean oil Glyceryl palmitostearate |
| Chemical description | Consists of a mixture of refined soybean oil, glyceryl distearate (C18) and polyglyceryl-3 dioleate (C18:1) |
| Food status | Soybean oil: food grade Glyceryl palmitostearate: FCC, GRAS 21 CFR §184.1329, JSFA |
Key characteristics
| Product form | Viscous gel |
|---|---|
| HLB | 5 |
Main functionalities
Vehicle to suspend pharmaceutical ingredients in soft gelatin capsule.
Good dispersibility in aqueous fluid.
High drug load achievable.
Thixotropic behavior: can be processed only by mixing—ideal for sensitive actives.
Safety of use is inferred by food additive status and precedence of use.
Main formulation technologies
Soft capsule filling
Associated content
Capsule filling and molding
Capsule filling and molding are common technologies suitable for powder, liquid,…
