Hard fat suppository base comprising polyoxylglyceride esters to enhance drug solubility and bioavailability.
Names & synonyms
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|---|---|
| EP Name | |
| UNII Code (FDA) | |
| Preferred Substance Name (FDA) | |
| Handbook of Pharmaceutical Excipients | Saturated polyglycolysed glycerides |
| Chemical description | Consists of of mono, di- and triglycerides and PEG mono- and di- esters of saturated fatty acids |
Key characteristics
| Product form | Pellets |
|---|---|
| Melting range (°C) | 33 - 35 |
| Hydroxyl value (mg KOH/g) | 30 - 60 |
Main functionalities
Optimized for solubility and bioavailability enhancement of poorly soluble APIs.
Main formulation technologies
Suppository molding.
Resources
Associated content
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