A glyceride with a high melting point used as a lubricant (low percentage). Compritol® E ATO can also be used as a modified release agent at a higher percentage: an ideal excipient for once-a-day nutraceutical administration.
Names & synonyms
| INCI name | Glyceryl behenate |
|---|---|
| Chemical name and synonyms |
|
| Food additive names |
|
| CAS Number | 77538-19-3 |
| EINECS Number | 278-717-5 |
Key characteristics
| Product form | Atomized powder |
|---|---|
| Melting point | 75°C |
| Quality compliance | Manufactured according HACCP |
| Regulatory compliance* |
|
| Certifications** |
|
*Please ensure to check the regulations applicable in your country
**Please enquire for more information
Main functionalities
At a low dose (1 to 3%), Compritol® E ATO can be used as a lubricant for tablet or hard capsule dosage forms.
At a higher dose (10-20%), Compritol® E ATO can be used as a modified-release agent to ensure a ‘once daily’ dose, ideal to increase compliance and product efficacy.
Examples of dietary ingredients that can be formulated include hydrophilic vitamins, minerals, plant extracts, probiotics.
Main formulation technologies
As a lubricant, Compritol® E ATO is added to the final mix just before compression.
As a sustained-release agent, Compritol® E ATO is added at the beginning of the formulation processes, such as granulation (hot or wet) or hot-melt extrusion.
Resources
Associated content
Markets
Gattefossé is providing innovative excipients for all routes of administration,…
Excipients for modified release
Modified- or sustained-release matrices are designed to release a drug slowly over…
Excipients for lubrication
During tablet and capsule production, lubricants are necessary to improve powder…