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Implementation of an at-line nanoparticle size analyzer in a continuous nano-manufacturing line considering critical measurement and process conditions

  • Poster

PBP - Mar 2024

C. Glader, R. Jeitler, N. Cacic, Y. Wang, C. Tetyczka, M. Zettl, J. Khinast, M. Rossano, S. Mesite, M. Lübbert, E. Roblegg

Nanopharmaceuticals' size is a critical quality attribute. This work provides insights about the implementation of an at-line particle size analyzer in a continuous manufacturing line of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC).

Formulation Components' Role in Shaping Continuous Nanocarrier Production through Impingement Jet Mixing

  • Poster

PBP - Mar 2024

C. Tetyczka, M. Zettl, C. Glader, R. Jeitler, S. Stephan, M. Segl, Y. Wang, P. Caisse, V. Bourgeaux, M. Spoerk, J. Khinast, E. Roblegg

Flash nanoemulsification with impingement jet mixing is a technique used to produce nanocarriers. This study optimized the nanocarrier formulation to facilitate the manufacturing process and monitoring.

Precision Engineering of Lipid-Based Nanosystems via Impingement Jet Mixing

  • Poster

PBP - Mar 2024

M. Zettl, C. Tetyczka, C. Glader, R. Jeitler, S. Stephan, M. Segl, Y. Wang, P. Caisse, V. Bourgeaux, M. Spoerk, E. Roblegg, J. Khinast

Advantages of combining polymers and lipids in extrusion processes

  • Poster

PBP - Mar 2024

Ceren Yüce, Lolie Cheron, Anja Geissler-Fichtner, Elsa Gattefossé

Lipid excipients lower the glass transition temperature of polymers, enabling hot-melt extrusion at lower engine torque for better processability. Different polymers and lipid combinations have been tested to explore their potential in extrusion processes.

Formulating pharmaceutical topical dosage forms with high level of solvents and minimal quantity of water

  • Poster

PBP - Mar 2024

Delphine Pélisson, Elise Dauphin-Chanard

This poster dives into the formulation of topical dosage forms containing the maximum amount of solvent and the minimum amount of water, while ensuring their stability upon storage.

Labrafac™ N MB

Medium-chain triglycerides
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Geleol™ N MB

Glyceryl palmitostearate E 471 / GRAS
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Compritol® E ATO

Glyceryl dibehenate E 471 / GRAS
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RevitaGlow Concealer

2886-1.04

An hybrid Skincare x Makeup concealer, anti-fatigue and anti-wrinkle.

Revitaglow concealer
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